Action potential–independent spontaneous microdomain Ca2+ transients–mediated continuous neurotransmission regulates hyperalgesia

Proceedings of the National Academy of Sciences, Volume 122, Issue 3, January 2025. <br/>SignificanceThe neurotransmission between dorsal root ganglion (DRG) and spinal cord neurons is essential for pain sensation. Mounting evidence has established the crucial roles of action potential (AP)-evoked neurotransmission from DRG neurons in chronic ...